Tretinoin

What is Tretinoin?

Tretinoin is an ATRA (All trans-retinoic acid) by nature. Retinoic acids are metabolites of Vitamin-A used for growth and development. Tretinoin cream is a chemically synthesized Vitamin-A derivative used for epithelial cell growth in humans. It is available in a 0.025% concentration in jelly, cream, or lotion form.

What is Tretinoin cream used for?

The cream is used for the treatment of acne or other skin disorders as per the advice of the medical practitioner. It is most commonly available by the name of Retin-A in Australia. Apart from acne, it is also helpful in fighting the effects of sun damage or wrinkles. It can be used either on its own or in combination with other medications or skin care products. Cystic acne and acne scars have shown the best results when treated with medication.

Are Tretinoin and Retinol the same?

Tretinoin and Retinol are both Vitamin A derivatives. But they are not the same. Retinoids are naturally derived Vitamin A derivatives that are available without a prescription. It can be obtained in a lot of over-the-counter shops dealing with cosmetic products. Tretinoin is a synthetic version of vitamin A and is available only through prescription. Additionally, they are not suitable for all skin types.

How does Tretinoin cream work?

The exact mechanism of Tretinoin cream is still under research. But it had been postulated by researchers that it blocks the inflammatory receptors and binds to the Retinoic acid receptors to bring out its effectiveness. The drug modifies abnormal follicular formation as a result of excessive keratinization of epithelial cells. It promotes cornified cell detachment and enhances shedding as a part of its acne treatment mechanism.

How long does Tretinoin cream take to produce results?

It depends on the frequency of using the cream. When used on a daily basis, it takes 6 weeks for the results to start being evident. When used every 2-3 days, it takes around 10 weeks for visible results. When used on a weekly basis, it takes 3 months for the medication to start showing results. Initially, there is mild irritation because of rough skin foliation that is followed by an increase in healing effects.

Does Retin-a cream start work immediately?

The first 2-4 weeks of using the cream result in a flakiness or slight increase in the acne intensity that is a part of the medication working on the skin cells. After 4-6 weeks, the medication settles down and the optimization process of the skin begins in full force. Within 12 weeks there is marked improvement noticed in the skin quality with a decrease in the size of oil glands and pores. After 6 months, collagen production is marked giving rise to smoother and more radiant skin.

How to use Tretinoin cream for best results?

Clean the face before application of the cream and dry it before use. Apply the cream in a thin layer on the acne-prone skin. This should be done daily at bedtime for a duration advised by the doctor or as long as the breakouts last. Wait for 20-30 minutes till the skin is completely dry before applying it. Do not use cosmetics over the cream

How can I buy Tretinoin cream in Australia?

Tretinoin cream in Australia is strictly a prescription medication and not available for sale over the counter. You will need to consult a healthcare practitioner and obtain a prescription for your skin condition to obtain it. Registered pharmacies and physicians’ clinics are some of the common places where you can obtain the cream. It can also be availed through online portals.

What are the things to remember while buying Tretinoin cream in Australia?

Tretinoin cream comes in strengths of 0.005%, 0.025%, 0.05%, and 0.1%. It is important to know the exact strength of the cream advised by your medical practitioner and purchase it accordingly. Tretinoin gels are also available and should not be confused with the cream. Additionally, lotion versions are also available that contain the lowest concentration of Tretinoin medication.

What is the difference between Tretinoin cream and Tretinoin gel?

Tretinoin creams are thicker and contain the highest levels of the medication. They take time to show results but are safer and more skin-friendly in the long run. Tretinoin gels are transparent and less concentrated than the cream versions. They tend to show quicker results but can irritate the skin more than cream versions.

Can I buy Tretinoin cream online in Australia?

Tretinoin creams can be obtained online in Australia through a physician’s prescription. Online ordering ensures faster and more efficient delivery of medication in a hassle-free manner. While ordering, read the online reviews carefully before the purchase. This will help understand the authenticity of the site and enable you to obtain genuine medication. Also, select the concentration carefully before ordering it so you get the correct strength

What are the side effects associated with the use of Tretinoin?

The side effects associated with Tretinoin cream use are- burning or tingling sensation of varying intensity, chapping or feeling of the skin of varying intensities, redness, and unusually warm skin.

Sometimes there is unexpected lightening of the treated skin area with a tendency of the skin during this time to easily sunburn. Occasionally the reverse occurs and the treated skin darkens or shows hyperpigmentation.

Who should not use Tretinoin?

Tretinoin should not be used by pregnant or breastfeeding ladies or in women trying to get pregnant. It is strictly contraindicated in people with eczema or other chronic skin conditions, especially on the face. Additionally, it should not be used in people with sunburn tendencies or light sensitivity or those taking photosynthesizing drugs.

Are there any drug interactions with Tretinoin?

Some of the drug interactions of Tretinoin cream are:

With Aminolevulinic acid

Concomitant use of the two leads to photosensitivity reactions and increases the risk of severe sunburn.

With Isotretinoin

Using the two together, especially in people with skin sensitivity can lead to further sensitivity problems and increase skin irritation.

With Salicylic acid and Benzoyl peroxide topical

Combined use of the two can lead to drying of the skin or excessive skin irritation.

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